what are the factors affecting posology - An Overview
what are the factors affecting posology - An Overview
Blog Article
Route of administration: The route of administration of a medication could also impression the posology. By way of example, medicines administered orally could demand better doses than All those administered intravenously on account of distinctions in bioavailability.
medicaments by using a chance of toxic reactions.
Beta-two receptors are most expressed from the bronchioles in the lungs and also the arteries of skeletal muscle mass; consequently, beta-2 agonists make the best consequences in these tissues and organs.
Increased excretion of metals besides iron: DF and L1 bring about increased aluminium excretion in renal dialysis patients.
General, many new and adjuvant therapies may very well be formulated and grow to be obtainable for the long run management of iron overload in chronically transfused individuals. These could involve the usage of new chelating drugs and optimal chelation therapy protocols for growing iron excretion, selected eating plans and therapies for inhibiting iron absorption and the usage of modulators for regulatory molecules involved with erythropoiesis and iron metabolism for instance activators of HbF creation, proteins affecting iron transportation, utilisation and storage, along with mixtures of such treatment options.
Dose: Amount of money administered or consumed by a affected individual to be able to get the desired clinical consequence. A patient's therapeutic benefit must be maximized Along with the least volume of medication.
Name your collection: Title has to be less than a hundred characters Select a collection: Not able to load your assortment as a consequence of an error
Since the drug detoxification and excretion mechanisms click here current within the fetus are underdeveloped, concentrations of drugs may possibly get to a higher degree while in the fetus than inside the maternal circulation.
is surely an inert substance, which does not have any therapeutic or poisonous house. Placebos are Employed in scientific trials to achieve some psychological results. Most often applied placebos are lactose tablet and distilled drinking water injections. Placebo effects are attained in angina more info and asthma
Only unbound drug is available for passive diffusion to extravascular or tissue web pages in which the pharmacologic results of your drug come about. Thus, the unbound drug focus in systemic circulation generally decides drug concentration on the Lively web page and thus efficacy.
Drug antagonism takes place when a person drug's activity is countered by A further drug's motion on precisely the same pharmacological procedure.
When acid poisoning is treated with milk of magnesia, the alkaline action of milk of magnesia neutralizes the effects of acid poisoning.
When two or more medicines are employed with each other, their consequences are Improved Because of this. Therefore, a phenomenon called synergism has produced.
A nearly impenetrable barricade that is crafted from the tightly woven mesh of capillaries cemented jointly to safeguard the brain from probably perilous substances like poisons or viruses.